Amakhowe anemiphumela yokuqinisa umzimba, i-tonifying qi, i-detoxifying, kanye ne-anti-cancer.I-polysaccharide yamakhowe iyisithako esisebenzayo esikhishwe emzimbeni othela izithelo we-Mushrooms, ikakhulukazi i-manan, i-glucan nezinye izakhi.Kuyi-agent ye-immunoregulatory.Ucwaningo luye lwabonisa ukuthi i-lentinan ivuselela amangqamuzana omzimba womuntu, ikhuthaza ukuhlukaniswa nokuhlukaniswa kwamangqamuzana omzimba omzimba, yandisa kakhulu i-lymphocyte, inomsebenzi oqinile wokulwa ne-tumor, futhi ingathuthukisa kakhulu umsebenzi wokuzivikela weziguli.Njengesiguquli sokuphendula sebhayoloji esihlanganiswe nokwelapha ngamakhemikhali okuvamile, singafinyelela injongo yokwelashwa kwe-adjuvant.
Iziguli zomdlavuza wesisu eziyi-150 ezingeniswe esibhedlela iYancheng First People’s kusukela ngoJanuwari kuya kuDisemba 2019 ziqokwe njengezifundo zocwaningo.Ngokwendlela yethebula lezinombolo ezingahleliwe, ahlukaniswa abe yiqembu elilawulayo neqembu lokufunda, ngamacala angama-75 eqenjini ngalinye.Iqembu elilawulayo lelashwa nge-chemotherapy, futhi iqembu locwaningo laphathwa nge-lentinan ngesisekelo seqembu elilawulayo.Ukusebenza kokuzivikela komzimba nokusebenza kahle komtholampilo ngaphambi nangemva kokwelashwa emaqenjini amabili kwaqhathaniswa, kanye nokusabela okubi kanye nekhwalithi yokuphila okubangelwa i-chemotherapy emaqenjini amabili ngemva kokwelashwa.
Ngemuva kokwelashwa, kwakungekho umehluko ophawulekayo wezibalo ezenzakalweni zokusebenza kwesibindi okungavamile phakathi kwamaqembu amabili (P> 0.05).Uma kuqhathaniswa neqembu lokulawula, umehluko ububalulekile ngokwezibalo (P<0.05)
Imiphumela yocwaningo ibonise ukuthi ngemva kokwelashwa, kwakungekho umehluko omkhulu ezenzweni zesibindi esingavamile phakathi kwamaqembu amabili (P> 0.05).Izinga lokuthuthukiswa kwekhwalithi laliphezulu kuneqembu lokulawula, futhi umehluko wawubalulekile ngokwezibalo (P<0.05).Kuphakanyiswa ukuthi i-lentinan inomphumela wokunciphisa ubuthi, obunganciphisa ubuthi nemiphumela engemihle ebangelwa ukwelapha ngamakhemikhali, ngaleyo ndlela kuthuthukiswe izinga lempilo yeziguli.Ngesikhathi esifanayo, imiphumela yalolu cwaningo ibonise ukuthi izinga eliphumelelayo lokwelashwa eqenjini locwaningo laliphakeme kuneqembu lokulawula, futhi umehluko wawubalulekile ngokwezibalo (P <0.05).Kuphakanyiswa ukuthi ekwelapheni umdlavuza wesisu, i-lentinan adjuvant therapy ingathuthukisa ukusebenza kahle komtholampilo.
Kuye kwahlaziywa ukuthi i-lentinan inemiphumela elandelayo kumdlavuza wesisu:①Ingakhuthaza ukuvuthwa kwama-lymphocyte T, ithuthukise umsebenzi wamaseli e-NK, bese ithuthukisa amandla okubulala amangqamuzana omdlavuza;②Ingaheha ama-macrophages ukukhombisa umsebenzi wokuzivikela komzimba., ingaqhubeka ibulale amangqamuzana omdlavuza;③It cukunciphisa ubuthi nemiphumela engemihle ebangelwa ukwelapha ngamakhemikhali, ukuthuthukisa izinga lempilo yeziguli;④Ingakwazi ithuthukisa umphumela we-chemotherapy.
imikhiqizo ehlobene ihlanganisaI-shiitake Mushroom Extract
Isikhathi sokuthumela: May-07-2022